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HYGEIA 10-Point Biotech VC Checklist


 

The “Great Biotech Reset” is here. Capital is scarce, and the margin for error is zero. Yet, most VCs are still getting blindsided by the same operational failures: flawed trial designs, weak CRO contracts, and founder-operators who can’t scale.

 

The Problem:

We analyzed 100+ biotech investment memos. The pattern was clear: the “VC Operational Blindspot” is where promising science becomes a portfolio write-down.

 

The Solution:

So, we built a tool to close that gap. We’ve distilled 20+ years of CRO leadership into a single page.

 

🎯 Introducing: “The Operational Due Diligence Checklist: 10 Red Flags VCs Miss Before Signing a Term Sheet.”

This isn’t another theoretical framework. It’s the same practical checklist we use in our 4-week,  Due-Diligence Sprints for top-tier funds.

 Inside, you’ll learn how to spot:

✓ The “Hockey Stick” Runway Model that hides cash burn.
✓ Flawed Clinical Trial Designs that produce unconvincing data.
✓ Weak CRO Contracts with no performance clawbacks.
✓ The “Portfolio Black Box” hiding your asset’s true health.

 

This checklist is the tactical companion to our widely-shared White Paper, “The Great Biotech Reset.” It’s built for one purpose: to help you identify deal-killing operational flaws before you commit capital.

 

Ready to de-risk your next investment?

⬇️ DOWNLOAD THE CHECKLIST HERE ⬇️

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